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Chemokine-Releasing Nanoparticles for Manipulation of the Lymph Node Microenvironment

Chemokines (CKs) secreted by the host cells into surrounding tissue establish concentration gradients directing the migration of leukocytes. We propose an in vivo CK gradient remodeling approach based on sustained release of CKs by the crosslinked poly(N-isopropylacrylamide) hydrogel open meshwork n...

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Detalles Bibliográficos
Autores principales: Popova, Taissia G., Teunis, Allison, Magni, Ruben, Luchini, Alessandra, Espina, Virginia, Liotta, Lance A., Popov, Serguei G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394634/
https://www.ncbi.nlm.nih.gov/pubmed/25878893
http://dx.doi.org/10.3390/nano5010298