HIF-inducible miR-191 promotes migration in breast cancer through complex regulation of TGFβ-signaling in hypoxic microenvironment.

The molecular mechanisms of hypoxia induced breast cell migration remain incompletely understood. Our results show that hypoxia through hypoxia-inducible factor (HIF) brings about a time-dependent increase in the level of an oncogenic microRNA, miR-191 in various breast cancer cell lines. miR-191 en...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagpal, Neha, Ahmad, Hafiz M., Chameettachal, Shibu, Sundar, Durai, Ghosh, Sourabh, Kulshreshtha, Ritu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394754/
https://www.ncbi.nlm.nih.gov/pubmed/25867965
http://dx.doi.org/10.1038/srep09650

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394754/
https://www.ncbi.nlm.nih.gov/pubmed/25867965
http://dx.doi.org/10.1038/srep09650

Ejemplares similares