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Poly (ADP-ribose) polymerase- and cytochrome c-mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia-induced hepatic failure

Hepatic failure (HF) is caused by several factors, which induce liver cell damage and dysfunction. However, the specific mechanism of HF remains to be fully elucidated. The present study aimed to investigate the underlying cause of hepatocyte injury and liver dysfunction. Liver cells were isolated f...

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Detalles Bibliográficos
Autores principales: GAO, GUANMIN, YU, ZUJIANG, YAN, JINGYA, LI, JINGJING, SHEN, SHEN, JIA, BIN, GUAN, KELEI, GAO, XIAOJUAN, KAN, QUANCHENG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394961/
https://www.ncbi.nlm.nih.gov/pubmed/25634059
http://dx.doi.org/10.3892/mmr.2015.3281