Cargando…

Poly (ADP-ribose) polymerase- and cytochrome c-mediated apoptosis induces hepatocyte injury in a rat model of hyperammonia-induced hepatic failure

Hepatic failure (HF) is caused by several factors, which induce liver cell damage and dysfunction. However, the specific mechanism of HF remains to be fully elucidated. The present study aimed to investigate the underlying cause of hepatocyte injury and liver dysfunction. Liver cells were isolated f...

Descripción completa

Detalles Bibliográficos
Autores principales:	GAO, GUANMIN, YU, ZUJIANG, YAN, JINGYA, LI, JINGJING, SHEN, SHEN, JIA, BIN, GUAN, KELEI, GAO, XIAOJUAN, KAN, QUANCHENG
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2015
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394961/ https://www.ncbi.nlm.nih.gov/pubmed/25634059 http://dx.doi.org/10.3892/mmr.2015.3281

Ejemplares similares

Hyperammonia induces specific liver injury through an intrinsic Ca(2+)-independent apoptosis pathway
por: Li, Jingjing, et al.
Publicado: (2014)

RNA regulation by Poly(ADP-ribose) polymerases
por: Bock, Florian J., et al.
Publicado: (2015)

Mitotic functions of poly(ADP-ribose) polymerases
por: Slade, Dea
Publicado: (2019)

The Antiviral Activities of Poly-ADP-Ribose Polymerases
por: Malgras, Mathilde, et al.
Publicado: (2021)

The role of poly (ADP-ribose) polymerase in ventilator-induced lung injury
por: Vaneker, Michiel, et al.
Publicado: (2008)

Poly (ADP-Ribose) Polymerase Mediates Diabetes-Induced Retinal Neuropathy
por: Mohammad, Ghulam, et al.
Publicado: (2013)

Pharmacological inhibition of poly (ADP-ribose) polymerase by olaparib ameliorates influenza-virus-induced pneumonia in mice
por: Liu, Wei, et al.
Publicado: (2020)

Effect and mechanism of poly (ADP-ribose) polymerase-1 in aldosterone-induced apoptosis
por: QIAO, WEIWEI, et al.
Publicado: (2015)

Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
por: Vormoor, Britta, et al.
Publicado: (2014)

Role of poly(ADP-ribose) polymerases in male reproduction
por: Celik-Ozenci, Ciler, et al.
Publicado: (2013)

Inhibition of Poly ADP-Ribose Glycohydrolase Sensitizes Ovarian Cancer Cells to Poly ADP-Ribose Polymerase Inhibitors and Platinum Agents
por: Matanes, Emad, et al.
Publicado: (2021)

Stability of centrosome numbers in poly(ADP-ribose) polymerase-1- and poly(ADP-ribose) glycohydrolase-deficient mouse ES cells
por: Ogino, Hideki, et al.
Publicado: (2004)

Poly(ADP-ribose)polymerases inhibitors prevent early mitochondrial fragmentation and hepatocyte cell death induced by H(2)O(2)
por: Martín-Guerrero, Sandra M., et al.
Publicado: (2017)

Inflammatory and transcriptional roles of poly (ADP-ribose) polymerase in ventilator-induced lung injury
por: Kim, Je Hyeong, et al.
Publicado: (2008)

Pancreatic β-Cell Death, Regeneration and Insulin Secretion: Roles of Poly(ADP-Ribose) Polymerase and Cyclic ADP-Ribose
por: Takasawa, Shin, et al.
Publicado: (2002)

Loss of amplified genes by poly(ADP-ribose) polymerase inhibitors.
por: Nagao, M, et al.
Publicado: (1991)

Targeting poly(ADP-ribose) polymerase activity for cancer therapy
por: Mégnin-Chanet, Frédérique, et al.
Publicado: (2010)

Lipoxygenases and Poly(ADP-Ribose) Polymerase in Amyloid Beta Cytotoxicity
por: Strosznajder, Joanna B., et al.
Publicado: (2011)

Analysis of Poly(ADP-Ribose) Polymerases in Arabidopsis Telomere Biology
por: Boltz, Kara A., et al.
Publicado: (2014)

The Role of Poly(ADP-ribose) Polymerase-1 in Rheumatoid Arthritis
por: García, Samuel, et al.
Publicado: (2015)

Poly (ADP-ribose) polymerase inhibitors in the management of ovarian cancer
por: Markman, Maurie
Publicado: (2018)

Poly(ADP-Ribose)Polymerase (PARP) Inhibitors and Radiation Therapy
por: Jannetti, Stephen A., et al.
Publicado: (2020)

Poly(ADP-Ribose) Polymerase-3 Regulates Regeneration in Planarians
por: Barghouth, Paul G., et al.
Publicado: (2020)

New Facets in the Regulation of Gene Expression by ADP-Ribosylation and Poly(ADP-ribose) Polymerases
por: Ryu, Keun Woo, et al.
Publicado: (2015)

Characterization of TCDD-inducible poly-ADP-ribose polymerase (TIPARP/ARTD14) catalytic activity
por: Gomez, Alvin, et al.
Publicado: (2018)

Radiation-induced neuroinflammation: a potential protective role for poly(ADP-ribose) polymerase inhibitors?
por: Gutierrez-Quintana, Rodrigo, et al.
Publicado: (2022)

TCDD-inducible Poly (ADP-ribose) Polymerase Promotes Adipogenesis of Both Brown and White Preadipocytes
por: Liu, Lingchao, et al.
Publicado: (2022)

Identification of probe-quality degraders for Poly(ADP-ribose) polymerase-1 (PARP-1)
por: Zhang, Zhimin, et al.
Publicado: (2020)

Background-Quenched Aggregation-Induced Emission through Electrostatic Interactions for the Detection of Poly(ADP-ribose) Polymerase-1 Activity
por: Gao, Fengli, et al.
Publicado: (2023)

Poly(ADP-ribose) polymerase inhibitor development: are we in the right direction?
por: Plummer, R
Publicado: (2011)

Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes
por: Citarelli, Matteo, et al.
Publicado: (2010)

Poly(ADP-Ribose) Polymerase 1: Cellular Pluripotency, Reprogramming, and Tumorogenesis
por: Jiang, Bo-Hua, et al.
Publicado: (2015)

Multiple facets of poly(ADP-ribose) polymerase-1 in neurological diseases
por: Sriram, Chandra Shaker, et al.
Publicado: (2015)

The promising role of poly(ADP-ribose) polymerase inhibitors in prostate cancer
por: Aragon-Ching, Jeanny B
Publicado: (2016)

Update on Poly-ADP-ribose polymerase inhibition for ovarian cancer treatment
por: Papa, Anselmo, et al.
Publicado: (2016)

Current status of poly(ADP-ribose) polymerase inhibitors and future directions
por: Ohmoto, Akihiro, et al.
Publicado: (2017)

Poly(ADP-Ribose) Polymerases in Plants and Their Human Counterparts: Parallels and Peculiarities
por: Rissel, Dagmar, et al.
Publicado: (2019)

Poly (ADP-Ribose) Polymerase Inhibitors: Talazoparib in Ovarian Cancer and Beyond
por: Boussios, Stergios, et al.
Publicado: (2020)

Nanoparticle Formulations of Poly (ADP-ribose) Polymerase Inhibitors for Cancer Therapy
por: Singh, Bijay, et al.
Publicado: (2020)

Developmental changes of poly(ADP-ribose) polymerase expression in Sarcophaga peregrina
por: Masutani, Mitsuko, et al.
Publicado: (2004)

Cannot write session to /tmp/vufind_sessions/sess_20gnuv3iokt4run68evl6h76qb