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A long-acting β(2)-adrenergic agonist increases the expression of muscarine cholinergic subtype-3 receptors by activating the β(2)-adrenoceptor cyclic adenosine monophosphate signaling pathway in airway smooth muscle cells

The persistent administration of β(2)-adrenergic (β(2)AR) agonists has been demonstrated to increase the risk of severe asthma, partly due to the induction of tolerance to bronchoprotection via undefined mechanisms. The present study investigated the potential effect of the long-acting β(2)-adrenerg...

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Detalles Bibliográficos
Autores principales: LIU, YUAN-HUA, WU, SONG-ZE, WANG, GANG, HUANG, NI-WEN, LIU, CHUN-TAO
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394984/
https://www.ncbi.nlm.nih.gov/pubmed/25672589
http://dx.doi.org/10.3892/mmr.2015.3307