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A long-acting β(2)-adrenergic agonist increases the expression of muscarine cholinergic subtype-3 receptors by activating the β(2)-adrenoceptor cyclic adenosine monophosphate signaling pathway in airway smooth muscle cells
The persistent administration of β(2)-adrenergic (β(2)AR) agonists has been demonstrated to increase the risk of severe asthma, partly due to the induction of tolerance to bronchoprotection via undefined mechanisms. The present study investigated the potential effect of the long-acting β(2)-adrenerg...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394984/ https://www.ncbi.nlm.nih.gov/pubmed/25672589 http://dx.doi.org/10.3892/mmr.2015.3307 |