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GST M1-T1 null Allele Frequency Patterns in Geographically Assorted Human Populations: A Phylogenetic Approach

Genetic diversity in drug metabolism and disposition is mainly considered as the outcome of the inter-individual genetic variation in polymorphism of drug-xenobiotic metabolizing enzyme (XME). Among the XMEs, glutathione-S-transferases (GST) gene loci are an important candidate for the investigation...

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Detalles Bibliográficos
Autores principales: Kasthurinaidu, Senthilkumar Pitchalu, Ramasamy, Thirumurugan, Ayyavoo, Jayachitra, Dave, Dhvani Kirtikumar, Adroja, Divya Anantray
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395045/
https://www.ncbi.nlm.nih.gov/pubmed/25867025
http://dx.doi.org/10.1371/journal.pone.0118660