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Osmostress-Induced Apoptosis in Xenopus Oocytes: Role of Stress Protein Kinases, Calpains and Smac/DIABLO
Hyperosmotic shock induces cytochrome c release and capase-3 activation in Xenopus oocytes, but the regulators and signaling pathways involved are not well characterized. Here we show that hyperosmotic shock induces rapid calpain activation and high levels of Smac/DIABLO release from the mitochondri...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395108/ https://www.ncbi.nlm.nih.gov/pubmed/25866890 http://dx.doi.org/10.1371/journal.pone.0124482 |