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Osmostress-Induced Apoptosis in Xenopus Oocytes: Role of Stress Protein Kinases, Calpains and Smac/DIABLO

Hyperosmotic shock induces cytochrome c release and capase-3 activation in Xenopus oocytes, but the regulators and signaling pathways involved are not well characterized. Here we show that hyperosmotic shock induces rapid calpain activation and high levels of Smac/DIABLO release from the mitochondri...

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Detalles Bibliográficos
Autores principales: Messaoud, Nabil Ben, Yue, Jicheng, Valent, Daniel, Katzarova, Ilina, López, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395108/
https://www.ncbi.nlm.nih.gov/pubmed/25866890
http://dx.doi.org/10.1371/journal.pone.0124482