Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast

Genetic instability is a hallmark of aneuploidy in budding and fission yeast. All aneuploid yeast strains analyzed to date harbor elevated levels of Rad52-GFP foci, a sign of DNA damage. Here we investigate how continuously elevated levels of DNA damage affect aneuploid cells. We show that Rad52-GFP...

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Detalles Bibliográficos
Autores principales: Blank, Heidi M., Sheltzer, Jason M., Meehl, Colleen M., Amon, Angelika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395125/
https://www.ncbi.nlm.nih.gov/pubmed/25694455
http://dx.doi.org/10.1091/mbc.E14-10-1442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395125/
https://www.ncbi.nlm.nih.gov/pubmed/25694455
http://dx.doi.org/10.1091/mbc.E14-10-1442

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