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Mitotic entry in the presence of DNA damage is a widespread property of aneuploidy in yeast
Genetic instability is a hallmark of aneuploidy in budding and fission yeast. All aneuploid yeast strains analyzed to date harbor elevated levels of Rad52-GFP foci, a sign of DNA damage. Here we investigate how continuously elevated levels of DNA damage affect aneuploid cells. We show that Rad52-GFP...
Autores principales: | Blank, Heidi M., Sheltzer, Jason M., Meehl, Colleen M., Amon, Angelika |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395125/ https://www.ncbi.nlm.nih.gov/pubmed/25694455 http://dx.doi.org/10.1091/mbc.E14-10-1442 |
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