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Cytoplasmic hGle1A regulates stress granules by modulation of translation

When eukaryotic cells respond to stress, gene expression pathways change to selectively export and translate subsets of mRNAs. Translationally repressed mRNAs accumulate in cytoplasmic foci known as stress granules (SGs). SGs are in dynamic equilibrium with the translational machinery, but mechanism...

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Detalles Bibliográficos
Autores principales: Aditi, Folkmann, Andrew W., Wente, Susan R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395128/
https://www.ncbi.nlm.nih.gov/pubmed/25694449
http://dx.doi.org/10.1091/mbc.E14-11-1523