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Drosophila CLIP-190 and mammalian CLIP-170 display reduced microtubule plus end association in the nervous system

Axons act like cables, electrically wiring the nervous system. Polar bundles of microtubules (MTs) form their backbones and drive their growth. Plus end–tracking proteins (+TIPs) regulate MT growth dynamics and directionality at their plus ends. However, current knowledge about +TIP functions, mostl...

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Detalles Bibliográficos
Autores principales: Beaven, Robin, Dzhindzhev, Nikola S., Qu, Yue, Hahn, Ines, Dajas-Bailador, Federico, Ohkura, Hiroyuki, Prokop, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395129/
https://www.ncbi.nlm.nih.gov/pubmed/25694447
http://dx.doi.org/10.1091/mbc.E14-06-1083