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Control of lipid organization and actin assembly during clathrin-mediated endocytosis by the cytoplasmic tail of the rhomboid protein Rbd2

Clathrin-mediated endocytosis (CME) is facilitated by a precisely regulated burst of actin assembly. PtdIns(4,5)P2 is an important signaling lipid with conserved roles in CME and actin assembly regulation. Rhomboid family multipass transmembrane proteins regulate diverse cellular processes; however,...

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Detalles Bibliográficos
Autores principales: Cortesio, Christa L., Lewellyn, Eric B., Drubin, David G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395130/
https://www.ncbi.nlm.nih.gov/pubmed/25694450
http://dx.doi.org/10.1091/mbc.E14-11-1540