PKCι interacts with Rab14 and modulates epithelial barrier function through regulation of claudin-2 levels

PKCι is essential for the establishment of epithelial polarity and the normal assembly of tight junctions. We find that PKCι knockdown does not compromise the steady-state distribution of most tight junction proteins but results in increased transepithelial resistance (TER) and decreased paracellula...

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Detalles Bibliográficos
Autores principales: Lu, Ruifeng, Dalgalan, Dogukan, Mandell, Edward K., Parker, Sara S., Ghosh, Sourav, Wilson, Jean M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395131/
https://www.ncbi.nlm.nih.gov/pubmed/25694446
http://dx.doi.org/10.1091/mbc.E14-12-1613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395131/
https://www.ncbi.nlm.nih.gov/pubmed/25694446
http://dx.doi.org/10.1091/mbc.E14-12-1613

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