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Effect of Lysyl Oxidase Inhibition on Angiotensin II-Induced Arterial Hypertension, Remodeling, and Stiffness

It is well accepted that angiotensin II (Ang II) induces altered vascular stiffness through responses including both structural and material remodeling. Concurrent with remodeling is the induction of the enzyme lysyl oxidase (LOX) through which ECM proteins are cross-linked. The study objective was...

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Detalles Bibliográficos
Autores principales: Eberson, Lance S., Sanchez, Pablo A., Majeed, Beenish A., Tawinwung, Supannikar, Secomb, Timothy W., Larson, Douglas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395147/
https://www.ncbi.nlm.nih.gov/pubmed/25875748
http://dx.doi.org/10.1371/journal.pone.0124013