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Effect of Lysyl Oxidase Inhibition on Angiotensin II-Induced Arterial Hypertension, Remodeling, and Stiffness
It is well accepted that angiotensin II (Ang II) induces altered vascular stiffness through responses including both structural and material remodeling. Concurrent with remodeling is the induction of the enzyme lysyl oxidase (LOX) through which ECM proteins are cross-linked. The study objective was...
Autores principales: | Eberson, Lance S., Sanchez, Pablo A., Majeed, Beenish A., Tawinwung, Supannikar, Secomb, Timothy W., Larson, Douglas F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395147/ https://www.ncbi.nlm.nih.gov/pubmed/25875748 http://dx.doi.org/10.1371/journal.pone.0124013 |
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