Common Variants of KCNJ10 Are Associated with Susceptibility and Anti-Epileptic Drug Resistance in Chinese Genetic Generalized Epilepsies

To explore genetic mechanism of genetic generalized epilepsies (GGEs) is challenging because of their complex heritance pattern and genetic heterogeneity. KCNJ10 gene encodes Kir4.1 channels and plays a major role in modulating resting membrane potentials in excitable cells. It may cause GGEs if mut...

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Detalles Bibliográficos
Autores principales: Guo, Yong, Yan, Kui Po, Qu, Qiang, Qu, Jian, Chen, Zi Gui, Song, Tao, Luo, Xiang-Ying, Sun, Zhong-Yi, Bi, Chang-Long, Liu, Jin-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395153/
https://www.ncbi.nlm.nih.gov/pubmed/25874548
http://dx.doi.org/10.1371/journal.pone.0124896

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395153/
https://www.ncbi.nlm.nih.gov/pubmed/25874548
http://dx.doi.org/10.1371/journal.pone.0124896

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