Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells

Human mesenchymal stem cells (hMSCs) are adult multipotent stem cells located in various tissues, including the bone marrow. In contrast to terminally differentiated somatic cells, adult stem cells must persist and function throughout life to ensure tissue homeostasis and repair. For this reason, th...

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Detalles Bibliográficos
Autores principales: Minieri, Valentina, Saviozzi, Silvia, Gambarotta, Giovanna, Lo Iacono, Marco, Accomasso, Lisa, Cibrario Rocchietti, Elisa, Gallina, Clara, Turinetto, Valentina, Giachino, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395188/
https://www.ncbi.nlm.nih.gov/pubmed/25619736
http://dx.doi.org/10.1111/jcmm.12387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395188/
https://www.ncbi.nlm.nih.gov/pubmed/25619736
http://dx.doi.org/10.1111/jcmm.12387

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