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Persistent DNA damage-induced premature senescence alters the functional features of human bone marrow mesenchymal stem cells
Human mesenchymal stem cells (hMSCs) are adult multipotent stem cells located in various tissues, including the bone marrow. In contrast to terminally differentiated somatic cells, adult stem cells must persist and function throughout life to ensure tissue homeostasis and repair. For this reason, th...
Autores principales: | Minieri, Valentina, Saviozzi, Silvia, Gambarotta, Giovanna, Lo Iacono, Marco, Accomasso, Lisa, Cibrario Rocchietti, Elisa, Gallina, Clara, Turinetto, Valentina, Giachino, Claudia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395188/ https://www.ncbi.nlm.nih.gov/pubmed/25619736 http://dx.doi.org/10.1111/jcmm.12387 |
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