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Mitochondrial proteomics with siRNA knockdown to reveal ACAT1 and MDH2 in the development of doxorubicin-resistant uterine cancer

Mitochondria are key organelles in mammary cells in responsible for a number of cellular functions including cell survival and energy metabolism. Moreover, mitochondria are one of the major targets under doxorubicin treatment. In this study, low-abundant mitochondrial proteins were enriched for prot...

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Detalles Bibliográficos
Autores principales: Lo, Yi-Wen, Lin, Szu-Ting, Chang, Shing-Jyh, Chan, Chia-Hao, Lyu, Kevin W, Chang, Jo-Fan, May, Eugenie Wong Soon, Lin, Dai-Ying, Chou, Hsiu-Chuan, Chan, Hong-Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395189/
https://www.ncbi.nlm.nih.gov/pubmed/25639359
http://dx.doi.org/10.1111/jcmm.12388