Simvastatin Modulates Mesenchymal Stromal Cell Proliferation and Gene Expression

Statins are widely used hypocholesterolemic drugs that block the mevalonate pathway, responsible for the biosysnthesis of cholesterol. However, statins also have pleiotropic effects that interfere with several signaling pathways. Mesenchymal stromal cells (MSC) are a heterogeneous mixture of cells t...

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Detalles Bibliográficos
Autores principales: Zanette, Dalila Lucíola, Lorenzi, Julio Cesar Cetrulo, Panepucci, Rodrigo Alexandre, Palma, Patricia Vianna Bonini, dos Santos, Daiane Fernanda, Prata, Karen Lima, Silva, Wilson Araújo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395223/
https://www.ncbi.nlm.nih.gov/pubmed/25874574
http://dx.doi.org/10.1371/journal.pone.0120137

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395223/
https://www.ncbi.nlm.nih.gov/pubmed/25874574
http://dx.doi.org/10.1371/journal.pone.0120137

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