A Fast and Scalable Kymograph Alignment Algorithm for Nanochannel-Based Optical DNA Mappings

Optical mapping by direct visualization of individual DNA molecules, stretched in nanochannels with sequence-specific fluorescent labeling, represents a promising tool for disease diagnostics and genomics. An important challenge for this technique is thermal motion of the DNA as it undergoes imaging...

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Detalles Bibliográficos
Autores principales: Noble, Charleston, Nilsson, Adam N., Freitag, Camilla, Beech, Jason P., Tegenfeldt, Jonas O., Ambjörnsson, Tobias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395267/
https://www.ncbi.nlm.nih.gov/pubmed/25875920
http://dx.doi.org/10.1371/journal.pone.0121905

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395267/
https://www.ncbi.nlm.nih.gov/pubmed/25875920
http://dx.doi.org/10.1371/journal.pone.0121905

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