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A Fast and Scalable Kymograph Alignment Algorithm for Nanochannel-Based Optical DNA Mappings
Optical mapping by direct visualization of individual DNA molecules, stretched in nanochannels with sequence-specific fluorescent labeling, represents a promising tool for disease diagnostics and genomics. An important challenge for this technique is thermal motion of the DNA as it undergoes imaging...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395267/ https://www.ncbi.nlm.nih.gov/pubmed/25875920 http://dx.doi.org/10.1371/journal.pone.0121905 |