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Cajal Body Proteins Differentially Affect the Processing of Box C/D scaRNPs

Small nuclear ribonucleoproteins (snRNPs), which are required for pre-mRNA splicing, contain extensively modified snRNA. Small Cajal body-specific ribonucleoproteins (scaRNPs) mediate these modifications. It is unknown how the box C/D class of scaRNPs localizes to Cajal Bodies (CBs). The processing...

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Detalles Bibliográficos
Autores principales: Enwerem, Isioma I., Wu, Guowei, Yu, Yi Tao, Hebert, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395269/
https://www.ncbi.nlm.nih.gov/pubmed/25875178
http://dx.doi.org/10.1371/journal.pone.0122348