CYK4 Promotes Antiparallel Microtubule Bundling by Optimizing MKLP1 Neck Conformation

Centralspindlin, a constitutive 2:2 heterotetramer of MKLP1 (a kinesin-6) and the non-motor subunit CYK4, plays important roles in cytokinesis. It is crucial for the formation of central spindle microtubule bundle structure. Its accumulation at the central antiparallel overlap zone is key for recrui...

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Detalles Bibliográficos
Autores principales: Davies, Tim, Kodera, Noriyuki, Kaminski Schierle, Gabriele S., Rees, Eric, Erdelyi, Miklos, Kaminski, Clemens F., Ando, Toshio, Mishima, Masanori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395295/
https://www.ncbi.nlm.nih.gov/pubmed/25875822
http://dx.doi.org/10.1371/journal.pbio.1002121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395295/
https://www.ncbi.nlm.nih.gov/pubmed/25875822
http://dx.doi.org/10.1371/journal.pbio.1002121

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