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CYK4 Promotes Antiparallel Microtubule Bundling by Optimizing MKLP1 Neck Conformation
Centralspindlin, a constitutive 2:2 heterotetramer of MKLP1 (a kinesin-6) and the non-motor subunit CYK4, plays important roles in cytokinesis. It is crucial for the formation of central spindle microtubule bundle structure. Its accumulation at the central antiparallel overlap zone is key for recrui...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395295/ https://www.ncbi.nlm.nih.gov/pubmed/25875822 http://dx.doi.org/10.1371/journal.pbio.1002121 |