Differential Adjuvant Activities of TLR7 and TLR9 Agonists Inversely Correlate with Nitric Oxide and PGE(2) Production

Activation of different pattern recognition receptors causes distinct profiles of innate immune responses, which in turn dictate the adaptive immune response. We found that mice had higher CD4(+) T cell expansion to an immunogen, ovalbumin, when coadministered with CpG than with CL097 in vivo. To ac...

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Detalles Bibliográficos
Autores principales: Lee, Jinhee, Martinez, Nuria, West, Kim, Kornfeld, Hardy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395302/
https://www.ncbi.nlm.nih.gov/pubmed/25875128
http://dx.doi.org/10.1371/journal.pone.0123165

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395302/
https://www.ncbi.nlm.nih.gov/pubmed/25875128
http://dx.doi.org/10.1371/journal.pone.0123165

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