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Differential Adjuvant Activities of TLR7 and TLR9 Agonists Inversely Correlate with Nitric Oxide and PGE(2) Production
Activation of different pattern recognition receptors causes distinct profiles of innate immune responses, which in turn dictate the adaptive immune response. We found that mice had higher CD4(+) T cell expansion to an immunogen, ovalbumin, when coadministered with CpG than with CL097 in vivo. To ac...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395302/ https://www.ncbi.nlm.nih.gov/pubmed/25875128 http://dx.doi.org/10.1371/journal.pone.0123165 |