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Bariatric Surgery in Morbidly Obese Insulin Resistant Humans Normalises Insulin Signalling but Not Insulin-Stimulated Glucose Disposal

AIMS: Weight-loss after bariatric surgery improves insulin sensitivity, but the underlying molecular mechanism is not clear. To ascertain the effect of bariatric surgery on insulin signalling, we examined glucose disposal and Akt activation in morbidly obese volunteers before and after Roux-en-Y gas...

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Detalles Bibliográficos
Autores principales: Chen, Mimi Z., Hudson, Claire A., Vincent, Emma E., de Berker, David A. R., May, Margaret T., Hers, Ingeborg, Dayan, Colin M., Andrews, Robert C., Tavaré, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395354/
https://www.ncbi.nlm.nih.gov/pubmed/25876175
http://dx.doi.org/10.1371/journal.pone.0120084