Cargando…
Bariatric Surgery in Morbidly Obese Insulin Resistant Humans Normalises Insulin Signalling but Not Insulin-Stimulated Glucose Disposal
AIMS: Weight-loss after bariatric surgery improves insulin sensitivity, but the underlying molecular mechanism is not clear. To ascertain the effect of bariatric surgery on insulin signalling, we examined glucose disposal and Akt activation in morbidly obese volunteers before and after Roux-en-Y gas...
Autores principales: | Chen, Mimi Z., Hudson, Claire A., Vincent, Emma E., de Berker, David A. R., May, Margaret T., Hers, Ingeborg, Dayan, Colin M., Andrews, Robert C., Tavaré, Jeremy M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395354/ https://www.ncbi.nlm.nih.gov/pubmed/25876175 http://dx.doi.org/10.1371/journal.pone.0120084 |
Ejemplares similares
-
Targeting Non-Small Cell Lung Cancer Cells by Dual Inhibition of the Insulin Receptor and the Insulin-Like Growth Factor-1 Receptor
por: Vincent, Emma E., et al.
Publicado: (2013) -
The role of insulin therapy and glucose normalisation in patients with acute coronary syndrome
por: Lipton, J. A., et al.
Publicado: (2011) -
Weight Loss After Bariatric Surgery Reverses Insulin-Induced Increases in Brain Glucose Metabolism of the Morbidly Obese
por: Tuulari, Jetro J., et al.
Publicado: (2013) -
Rapid Insulin-Mediated Increase in Microvascular Glycocalyx Accessibility in Skeletal Muscle May Contribute to Insulin-Mediated Glucose Disposal in Rats
por: Eskens, Bart J. M., et al.
Publicado: (2013) -
Impact of Incretin Hormone Receptors on Insulin-Independent Glucose Disposal in Model Experiments in Mice
por: Ovlund, Tina, et al.
Publicado: (2021)