Murine CMV-Induced Hearing Loss Is Associated with Inner Ear Inflammation and Loss of Spiral Ganglia Neurons

Congenital human cytomegalovirus (HCMV) occurs in 0.5–1% of live births and approximately 10% of infected infants develop hearing loss. The mechanism(s) of hearing loss remain unknown. We developed a murine model of CMV induced hearing loss in which murine cytomegalovirus (MCMV) infection of newborn...

Descripción completa

Detalles Bibliográficos
Autores principales: Bradford, Russell D., Yoo, Young-Gun, Golemac, Mijo, Pugel, Ester Pernjak, Jonjic, Stipan, Britt, William J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395355/
https://www.ncbi.nlm.nih.gov/pubmed/25875183
http://dx.doi.org/10.1371/journal.ppat.1004774

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395355/
https://www.ncbi.nlm.nih.gov/pubmed/25875183
http://dx.doi.org/10.1371/journal.ppat.1004774

Ejemplares similares