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Murine CMV-Induced Hearing Loss Is Associated with Inner Ear Inflammation and Loss of Spiral Ganglia Neurons
Congenital human cytomegalovirus (HCMV) occurs in 0.5–1% of live births and approximately 10% of infected infants develop hearing loss. The mechanism(s) of hearing loss remain unknown. We developed a murine model of CMV induced hearing loss in which murine cytomegalovirus (MCMV) infection of newborn...
Autores principales: | Bradford, Russell D., Yoo, Young-Gun, Golemac, Mijo, Pugel, Ester Pernjak, Jonjic, Stipan, Britt, William J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395355/ https://www.ncbi.nlm.nih.gov/pubmed/25875183 http://dx.doi.org/10.1371/journal.ppat.1004774 |
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