Genetic Analysis of Ligation-Induced Neointima Formation in an F2 Intercross of C57BL/6 and FVB/N Inbred Mouse Strains

OBJECTIVE: Proliferation and migration of vascular smooth muscle cells (SMCs) are central for arterial diseases including atherosclerosis and restenosis. We hypothesized that the underlying mechanisms may be modeled by carotid ligation in mice. In FVB/N inbred mice, ligation leads to abundant neoint...

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Detalles Bibliográficos
Autores principales: Östergren, Caroline, Shim, Jeong, Larsen, Jens Vinther, Nielsen, Lars Bo, Bentzon, Jacob F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395357/
https://www.ncbi.nlm.nih.gov/pubmed/25875831
http://dx.doi.org/10.1371/journal.pone.0121899

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395357/
https://www.ncbi.nlm.nih.gov/pubmed/25875831
http://dx.doi.org/10.1371/journal.pone.0121899

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