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Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aortic Valve

AIMS: Oxidative stress is present in and contributes to calcification of the aortic valve, but the driving factors behind the initiation of valve oxidative stress are not well understood. We tested whether the valve endothelium acts as an initiator and propagator of oxidative stress in aortic valve...

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Detalles Bibliográficos
Autores principales: Farrar, Emily J., Huntley, Geoffrey D., Butcher, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395382/
https://www.ncbi.nlm.nih.gov/pubmed/25874717
http://dx.doi.org/10.1371/journal.pone.0123257