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Endothelial-Derived Oxidative Stress Drives Myofibroblastic Activation and Calcification of the Aortic Valve
AIMS: Oxidative stress is present in and contributes to calcification of the aortic valve, but the driving factors behind the initiation of valve oxidative stress are not well understood. We tested whether the valve endothelium acts as an initiator and propagator of oxidative stress in aortic valve...
Autores principales: | Farrar, Emily J., Huntley, Geoffrey D., Butcher, Jonathan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395382/ https://www.ncbi.nlm.nih.gov/pubmed/25874717 http://dx.doi.org/10.1371/journal.pone.0123257 |
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