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Deletion of FADD in Macrophages and Granulocytes Results in RIP3- and MyD88-Dependent Systemic Inflammation

Myeloid cells, which include monocytes, macrophages, and granulocytes, are important innate immune cells, but the mechanism and downstream effect of their cell death on the immune system is not completely clear. Necroptosis is an alternate form of cell death that can be triggered when death receptor...

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Detalles Bibliográficos
Autores principales: Schock, Suruchi N., Young, Jennifer A., He, Tina H., Sun, Yuefang, Winoto, Astar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395384/
https://www.ncbi.nlm.nih.gov/pubmed/25874713
http://dx.doi.org/10.1371/journal.pone.0124391