Twisting Right to Left: A…A Mismatch in a CAG Trinucleotide Repeat Overexpansion Provokes Left-Handed Z-DNA Conformation

Conformational polymorphism of DNA is a major causative factor behind several incurable trinucleotide repeat expansion disorders that arise from overexpansion of trinucleotide repeats located in coding/non-coding regions of specific genes. Hairpin DNA structures that are formed due to overexpansion...

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Detalles Bibliográficos
Autores principales: Khan, Noorain, Kolimi, Narendar, Rathinavelan, Thenmalarchelvi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395422/
https://www.ncbi.nlm.nih.gov/pubmed/25876062
http://dx.doi.org/10.1371/journal.pcbi.1004162

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395422/
https://www.ncbi.nlm.nih.gov/pubmed/25876062
http://dx.doi.org/10.1371/journal.pcbi.1004162

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