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Nicotinamide Exacerbates Hypoxemia in Ventilator-Induced Lung Injury Independent of Neutrophil Infiltration

BACKGROUND: Ventilator-induced lung injury is a form of acute lung injury that develops in critically ill patients on mechanical ventilation and has a high degree of mortality. Nicotinamide phosphoribosyltransferase is an enzyme that is highly upregulated in ventilator-induced lung injury and exacer...

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Detalles Bibliográficos
Autores principales: Jones, Heather D., Yoo, Jeena, Crother, Timothy R., Kyme, Pierre, Ben-Shlomo, Anat, Khalafi, Ramtin, Tseng, Ching W., Parks, William C., Arditi, Moshe, Liu, George Y., Shimada, Kenichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395431/
https://www.ncbi.nlm.nih.gov/pubmed/25875775
http://dx.doi.org/10.1371/journal.pone.0123460