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TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse

The formation of an immunological synapse (IS) requires tight regulation of actin dynamics by many actin polymerizing/depolymerizing proteins. However, the significance of actin stabilization at the IS remains largely unknown. In this paper, we identify a novel function of TAGLN2—an actin-binding pr...

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Detalles Bibliográficos
Autores principales: Na, Bo-Ra, Kim, Hye-Ran, Piragyte, Indre, Oh, Hyun-Mee, Kwon, Min-Sung, Akber, Uroos, Lee, Hyun-Su, Park, Do-Sim, Song, Woo Keun, Park, Zee-Yong, Im, Sin-Hyeog, Rho, Mun-Chual, Hyun, Young-Min, Kim, Minsoo, Jun, Chang-Duk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395477/
https://www.ncbi.nlm.nih.gov/pubmed/25869671
http://dx.doi.org/10.1083/jcb.201407130