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TAGLN2 regulates T cell activation by stabilizing the actin cytoskeleton at the immunological synapse
The formation of an immunological synapse (IS) requires tight regulation of actin dynamics by many actin polymerizing/depolymerizing proteins. However, the significance of actin stabilization at the IS remains largely unknown. In this paper, we identify a novel function of TAGLN2—an actin-binding pr...
Autores principales: | Na, Bo-Ra, Kim, Hye-Ran, Piragyte, Indre, Oh, Hyun-Mee, Kwon, Min-Sung, Akber, Uroos, Lee, Hyun-Su, Park, Do-Sim, Song, Woo Keun, Park, Zee-Yong, Im, Sin-Hyeog, Rho, Mun-Chual, Hyun, Young-Min, Kim, Minsoo, Jun, Chang-Duk |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395477/ https://www.ncbi.nlm.nih.gov/pubmed/25869671 http://dx.doi.org/10.1083/jcb.201407130 |
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