G3BP1 promotes stress-induced RNA granule interactions to preserve polyadenylated mRNA

G3BP1, a target of TDP-43, is required for normal stress granule (SG) assembly, but the functional consequences of failed SG assembly remain unknown. Here, using both transformed cell lines and primary neurons, we investigated the functional impact of this disruption in SG dynamics. While stress-ind...

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Detalles Bibliográficos
Autores principales: Aulas, Anaïs, Caron, Guillaume, Gkogkas, Christos G., Mohamed, Nguyen-Vi, Destroismaisons, Laurie, Sonenberg, Nahum, Leclerc, Nicole, Parker, J. Alex, Vande Velde, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395486/
https://www.ncbi.nlm.nih.gov/pubmed/25847539
http://dx.doi.org/10.1083/jcb.201408092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395486/
https://www.ncbi.nlm.nih.gov/pubmed/25847539
http://dx.doi.org/10.1083/jcb.201408092

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