Phosphorylated ubiquitin chain is the genuine Parkin receptor

PINK1 selectively recruits Parkin to depolarized mitochondria for quarantine and removal of damaged mitochondria via ubiquitylation. Dysfunction of this process predisposes development of familial recessive Parkinson’s disease. Although various models for the recruitment process have been proposed,...

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Detalles Bibliográficos
Autores principales: Okatsu, Kei, Koyano, Fumika, Kimura, Mayumi, Kosako, Hidetaka, Saeki, Yasushi, Tanaka, Keiji, Matsuda, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395490/
https://www.ncbi.nlm.nih.gov/pubmed/25847540
http://dx.doi.org/10.1083/jcb.201410050

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395490/
https://www.ncbi.nlm.nih.gov/pubmed/25847540
http://dx.doi.org/10.1083/jcb.201410050

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