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FBN-1, a fibrillin-related protein, is required for resistance of the epidermis to mechanical deformation during C. elegans embryogenesis
During development, biomechanical forces contour the body and provide shape to internal organs. Using genetic and molecular approaches in combination with a FRET-based tension sensor, we characterized a pulling force exerted by the elongating pharynx (foregut) on the anterior epidermis during C. ele...
Autores principales: | Kelley, Melissa, Yochem, John, Krieg, Michael, Calixto, Andrea, Heiman, Maxwell G, Kuzmanov, Aleksandra, Meli, Vijaykumar, Chalfie, Martin, Goodman, Miriam B, Shaham, Shai, Frand, Alison, Fay, David S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395870/ https://www.ncbi.nlm.nih.gov/pubmed/25798732 http://dx.doi.org/10.7554/eLife.06565 |
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