The E3 ubiquitin ligase Trim7 mediates c-Jun/AP-1 activation by Ras signalling

The c-Jun/AP-1 transcription factor controls key cellular behaviours, including proliferation and apoptosis, in response to JNK and Ras/MAPK signalling. While the JNK pathway has been well characterised, the mechanism of activation by Ras was elusive. Here we identify the uncharacterised ubiquitin l...

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Detalles Bibliográficos
Autores principales: Chakraborty, Atanu, Diefenbacher, Markus E., Mylona, Anastasia, Kassel, Olivier, Behrens, Axel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395875/
https://www.ncbi.nlm.nih.gov/pubmed/25851810
http://dx.doi.org/10.1038/ncomms7782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395875/
https://www.ncbi.nlm.nih.gov/pubmed/25851810
http://dx.doi.org/10.1038/ncomms7782

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