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Rapid epigenetic adaptation to uncontrolled heterochromatin spreading

Heterochromatin, a highly compact chromatin state characterized by histone H3K9 methylation and HP1 protein binding, silences the underlying DNA and influences the expression of neighboring genes. However, the mechanisms that regulate heterochromatin spreading are not well understood. In this study,...

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Detalles Bibliográficos
Autores principales: Wang, Jiyong, Reddy, Bharat D, Jia, Songtao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4395908/
https://www.ncbi.nlm.nih.gov/pubmed/25774602
http://dx.doi.org/10.7554/eLife.06179