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Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models

BACKGROUND: Patients suffering from cancer are often treated with a range of chemotherapeutic agents, but the treatment efficacy varies greatly between patients. Based on recent popularisation of regularised regression models the goal of this study was to establish workflows for pharmacogenomic pred...

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Detalles Bibliográficos
Autores principales: Falgreen, Steffen, Dybkær, Karen, Young, Ken H, Xu-Monette, Zijun Y, El-Galaly, Tarec C, Laursen, Maria Bach, Bødker, Julie S, Kjeldsen, Malene K, Schmitz, Alexander, Nyegaard, Mette, Johnsen, Hans Erik, Bøgsted, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396063/
https://www.ncbi.nlm.nih.gov/pubmed/25881228
http://dx.doi.org/10.1186/s12885-015-1237-6