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Predicting response to multidrug regimens in cancer patients using cell line experiments and regularised regression models
BACKGROUND: Patients suffering from cancer are often treated with a range of chemotherapeutic agents, but the treatment efficacy varies greatly between patients. Based on recent popularisation of regularised regression models the goal of this study was to establish workflows for pharmacogenomic pred...
Autores principales: | Falgreen, Steffen, Dybkær, Karen, Young, Ken H, Xu-Monette, Zijun Y, El-Galaly, Tarec C, Laursen, Maria Bach, Bødker, Julie S, Kjeldsen, Malene K, Schmitz, Alexander, Nyegaard, Mette, Johnsen, Hans Erik, Bøgsted, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396063/ https://www.ncbi.nlm.nih.gov/pubmed/25881228 http://dx.doi.org/10.1186/s12885-015-1237-6 |
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