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Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling

INTRODUCTION: High-risk neuroblastoma (HR-NB) presenting with hematogenous metastasis is one of the most difficult cancers to cure. Patient survival is poor. Aggressive tumors contain populations of rapidly proliferating clonogens that exhibit stem cell properties, cancer stem cells (CSCs). Conceptu...

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Detalles Bibliográficos
Autores principales: Pandian, Vijayabaskar, Ramraj, Satishkumar, Khan, Faizan H, Azim, Tasfia, Aravindan, Natarajan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396071/
https://www.ncbi.nlm.nih.gov/pubmed/25888913
http://dx.doi.org/10.1186/s13287-015-0002-8