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Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling
INTRODUCTION: High-risk neuroblastoma (HR-NB) presenting with hematogenous metastasis is one of the most difficult cancers to cure. Patient survival is poor. Aggressive tumors contain populations of rapidly proliferating clonogens that exhibit stem cell properties, cancer stem cells (CSCs). Conceptu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396071/ https://www.ncbi.nlm.nih.gov/pubmed/25888913 http://dx.doi.org/10.1186/s13287-015-0002-8 |