Cargando…

Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling

INTRODUCTION: High-risk neuroblastoma (HR-NB) presenting with hematogenous metastasis is one of the most difficult cancers to cure. Patient survival is poor. Aggressive tumors contain populations of rapidly proliferating clonogens that exhibit stem cell properties, cancer stem cells (CSCs). Conceptu...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pandian, Vijayabaskar, Ramraj, Satishkumar, Khan, Faizan H, Azim, Tasfia, Aravindan, Natarajan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396071/ https://www.ncbi.nlm.nih.gov/pubmed/25888913 http://dx.doi.org/10.1186/s13287-015-0002-8

Ejemplares similares

Erratum to: Metastatic neuroblastoma cancer stem cells exhibit flexible plasticity and adaptive stemness signaling
por: Pandian, Vijayabaskar, et al.
Publicado: (2016)

Reorganization of metastamiRs in the evolution of metastatic aggressive neuroblastoma cells
por: Khan, Faizan H, et al.
Publicado: (2015)

Acquired genetic alterations in tumor cells dictate the development of high-risk neuroblastoma and clinical outcomes
por: Khan, Faizan H., et al.
Publicado: (2015)

RD3 loss dictates high-risk aggressive neuroblastoma and poor clinical outcomes
por: Khan, Faizan H., et al.
Publicado: (2015)

Serum-circulating miRNAs predict neuroblastoma progression in mouse model of high-risk metastatic disease
por: Ramraj, Satish Kumar, et al.
Publicado: (2016)

Cancer stem cells in neuroblastoma therapy resistance
por: Aravindan, Natarajan, et al.
Publicado: (2019)

Hormophysa triquerta polyphenol, an elixir that deters CXCR4- and COX2-dependent dissemination destiny of treatment-resistant pancreatic cancer cells
por: Aravindan, Sheeja, et al.
Publicado: (2016)

Polyphenols from marine brown algae target radiotherapy-coordinated EMT and stemness-maintenance in residual pancreatic cancer
por: Aravindan, Sheeja, et al.
Publicado: (2015)

Novel adjuvants from seaweed impede autophagy signaling in therapy-resistant residual pancreatic cancer
por: Aravindan, Sheeja, et al.
Publicado: (2015)

MicroRNAs in neuroblastoma tumorigenesis, therapy resistance, and disease evolution
por: Aravindan, Natarajan, et al.
Publicado: (2019)

Novel Synthetic Monoketone Transmute Radiation-Triggered NFκB-Dependent TNFα Cross-Signaling Feedback Maintained NFκB and Favors Neuroblastoma Regression
por: Aravindan, Sheeja, et al.
Publicado: (2013)

De novo regulation of RD3 synthesis in residual neuroblastoma cells after intensive multi-modal clinical therapy harmonizes disease evolution
por: Somasundaram, Dinesh Babu, et al.
Publicado: (2019)

Droplet digital PCR as an alternative to FISH for MYCN amplification detection in human neuroblastoma FFPE samples
por: Somasundaram, Dinesh Babu, et al.
Publicado: (2019)

Mesenchymal stem cells accelerated growth and metastasis of neuroblastoma and preferentially homed towards both primary and metastatic loci in orthotopic neuroblastoma model
por: Yu, Jiao-Le, et al.
Publicado: (2021)

Allogeneic stem cell transplantation for neuroblastoma
por: Sung, Ki Woong
Publicado: (2012)

Neuroblastoma stem cells and CFC1
por: Tsubota, Shoma, et al.
Publicado: (2017)

Optimization of a Neural Stem-Cell-Mediated Carboxylesterase/Irinotecan Gene Therapy for Metastatic Neuroblastoma
por: Gutova, Margarita, et al.
Publicado: (2016)

Normal Hematopoetic Stem and Progenitor Cells Can Exhibit Metabolic Flexibility Similar to Cancer Cells
por: Vlaski-Lafarge, Marija, et al.
Publicado: (2020)

Reversible Adaptive Plasticity: A Mechanism for Neuroblastoma Cell Heterogeneity and Chemo-Resistance
por: Chakrabarti, Lina, et al.
Publicado: (2012)

Molecular basis of ‘hypoxic’ breast cancer cell radio-sensitization: phytochemicals converge on radiation induced Rel signaling
por: Aravindan, Sheeja, et al.
Publicado: (2013)

Neuroblastoma Heterogeneity, Plasticity, and Emerging Therapies
por: Lundberg, Kristina Ihrmark, et al.
Publicado: (2022)

Ex Vivo Model of Neuroblastoma Plasticity
por: Schäfer, Paula, et al.
Publicado: (2023)

Autologous stem cell transplantation for the treatment of neuroblastoma in Korea.
por: Ryu, Kyung Ha, et al.
Publicado: (2003)

Multidrug Resistance and Cancer Stem Cells in Neuroblastoma and Hepatoblastoma
por: Alisi, Anna, et al.
Publicado: (2013)

Cancer Stem Cells and Their Interaction with the Tumor Microenvironment in Neuroblastoma
por: Garner, Evan F., et al.
Publicado: (2015)

Revealed: The spy who regulates neuroblastoma stem cells
por: Vora, Parvez, et al.
Publicado: (2014)

Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier
por: Bahmad, Hisham F., et al.
Publicado: (2019)

Engineered human mesenchymal stem cells for neuroblastoma therapeutics
por: Nieddu, Valentina, et al.
Publicado: (2019)

Flexibility of Neural Stem Cells
por: Remboutsika, Eumorphia, et al.
Publicado: (2011)

A Mechanism Linking Id2-TGFβ Crosstalk to Reversible Adaptive Plasticity in Neuroblastoma
por: Chakrabarti, Lina, et al.
Publicado: (2013)

Myeloablative treatment supported by autologous stem cell infusion with neuroblastoma.
por: Ryu, Kyung Ha, et al.
Publicado: (2003)

Targeting Neuroblastoma Stem Cells with Retinoic Acid and Proteasome Inhibitor
por: Hämmerle, Barbara, et al.
Publicado: (2013)

Stem Cell Markers in Neuroblastoma—An Emerging Role for LGR5
por: Forgham, Helen, et al.
Publicado: (2015)

CFC1 is a cancer stemness-regulating factor in neuroblastoma
por: Chikaraishi, Koji, et al.
Publicado: (2017)

Cancer Stem Cells and Neuroblastoma: Characteristics and Therapeutic Targeting Options
por: Veschi, Veronica, et al.
Publicado: (2019)

Ferroptosis Inducers Kill Mesenchymal Stem Cells Affected by Neuroblastoma
por: Li, Xiangze, et al.
Publicado: (2023)

Plasticity of spermatogonial stem cells
por: Cooke, Paul S, et al.
Publicado: (2015)

Neuroblastoma patient-derived xenograft cells cultured in stem-cell promoting medium retain tumorigenic and metastatic capacities but differentiate in serum
por: Persson, Camilla U., et al.
Publicado: (2017)

Non-small cell lung cancer stem/progenitor cells are enriched in multiple distinct phenotypic subpopulations and exhibit plasticity
por: Akunuru, S, et al.
Publicado: (2012)

High Energy Particle Radiation-associated Oncogenic Transformation in Normal Mice: Insight into the Connection between Activation of Oncotargets and Oncogene Addiction
por: Aravindan, Natarajan, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_c3mokj4mp3ubts8qtccakds5no