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Unraveling the Hygiene Hypothesis of helminthes and autoimmunity: origins, pathophysiology, and clinical applications

BACKGROUND: The Hygiene Hypothesis (HH) attributes the dramatic increase in autoimmune and allergic diseases observed in recent decades in Western countries to the reduced exposure to diverse immunoregulatory infectious agents. This theory has since largely been supported by strong epidemiological a...

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Detalles Bibliográficos
Autores principales: Versini, Mathilde, Jeandel, Pierre-Yves, Bashi, Tomer, Bizzaro, Giorgia, Blank, Miri, Shoenfeld, Yehuda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4396177/
https://www.ncbi.nlm.nih.gov/pubmed/25879741
http://dx.doi.org/10.1186/s12916-015-0306-7